Genomics

NHS England Genomics Education Programme

Genomics 101 Genomics in Healthcare

Genomics and Couselling Skills

Future Learn - A Clinician's Guide to Genomic Testing for Cancer (Solid Tumours)

NHS Learning Hub -  Introduction to Immune Checkpoint Inhibitors

GeNotes: Genomic notes for clinicians

Genomics Learning Passport for Nurses

Genomics Learning Passport for Midwives

Join the thousands of healthcare staff using the QGenome app

Clinicians across the East Midlands and East of England can now have genomic referral, risk assessment and testing guidance in the palm of their hand, thanks to an NHSE-funded app called QGenome. The app, which can be downloaded for iOS and Android devices (with a web-based version also available) is based on national guidelines including NHS England’s National Genomic Test Directory. The app currently supports clinicians in the areas of cancer, cardiology, renal, prenatal and primary care. Some feedback from clinicians currently using the app includes:

• “Incredibly useful. Feels like I have a Genetic Counsellor on my shoulder.”
• “For someone new to genomics it has been invaluable in understanding eligibility pathways and has improved my knowledge and ability to speak to patients about their concerns.”
• “User friendly. Great educational and clinical decision support tool.”

You can find out more, including how to download the app on the QGenome website.

To watch a demo of the app by Dr Anju Kulkarni (one of the creators), please click here. 

Important concepts in cancer cell biology and genetics - Training Science Communicated Ltd

Session 1 - Cancer cell biology

Session 2 - Targeted therapies

Session 3 - Immunotherapy

Session 4 - Precision cancer medicine

P1 (Includes session 1 & 2) - Click here to watch

P2 (Includes session 3 & 4) - Click here to watch

1. Introduction to cancer treatments
2. Using small molecules as cancer treatments
3. Using antibodies as cancer treatments
4. How does chemotherapy work?
5. Hormone therapy for cancer
6. Targeted cancer treatments
7. Kinase inhibitor cancer treatments
8. Immunotherapy
9. Immune checkpoint inhibitors
10. Living cells as cancer treatments

UKCGG Leaflets and Guidelines

Central and South GMSA

Germline Test Order Form

Mainstreaming test request form: R207, R208, R444 – breast, ovarian and prostate cancer

Record of Discussion

Discussing Germline Testing: A 10-Step Clinic Guide

Our Voices, Our Stories: Lived Experiences of Genomic Testing Webinar

The East GMSA

East GLH

East Genomics Cancer and genetics patient leaflet

Germline Test Order Form

Record of Discussion

East Genomics Clinician's Guide to Genomic Testing 

East Genomics Letter - Improving efficiency and appropriateness of genomic test referrals 

Discussing Germline Testing: A 10-Step Clinic Guide

CanRisk for Breast Cancer Training Session - NHS East Genomics August 2025

New ordering and reporting details for cancer testing at East Genomics, Cambridge

High grade ovarian cancers need reflex HRD testing - East Genomics

Communities of Practice

East Genomics are supporting 16 Genomics Communities of Practice to support healthcare staff across specialities and job roles to share best practice, upskill and better integrate genomic medicine into their clinical practice.

For cancer these include:

Urology / Lung / CUP / Paediatric, teenage & young adult haemato-oncology / Pancreatic / Haemato-oncology / Gynaecological Oncology.

This link will take you to view each of the Communities of Practice including who is leading it, a schedule of upcoming meetings, how to join, and where to access slides and recordings from previous meetings

https://www.eastgenomics.nhs.uk/for-healthcare-professionals/east-genomics-communities-of-practice/

The North Thames GMSA

North Thames GLH

Germline test order form

Record of Discussion form

Discussing Germline Testing: A 10-Step Clinic Guide

How to Request Genetic Testing for Your Patients

Lynch Syndrome

Poster / PowerPoint  / Germline testing guide / Colorectal flowchart / Endometrial flowchart 

Genetic testing for Lynch Syndrome :: East of England Cancer Alliance

NHS East Genomics Lynch Syndrome app

UKCCG guidelines 2025 FAQ for Management Guidelines for MLH1, MSH2, MSH6, and PMS2 Germline

Aspirin and Lynch Syndrome – Frequently Asked Questions (FAQ) for People with Lynch Syndrome

Breast

PowerPoint / Germline Testing for Breast Cancer

Prostate

Germline testing in Prostate Cancer

The Royal Marsden - A beginner's guide to BRCA1 and BRCA2

BReast CAncer Genes and Me

NHS England - Cancer Vaccine Launch Pad

The NHS England Cancer Vaccine Launch Pad (CVLP)  is a platform facilitating access to clinical trials of cancer vaccines, with the aim to accelerate the development of cancer vaccines and increase the opportunity for patients to take part in cancer vaccine trials. The CVLP is being set up in a phased approach to support multiple industry partners with new cancer vaccines across a broad range of cancer types, this started with a focus on patients with colorectal cancer.

The opportunity to be a recruitment centre for the Cancer Vaccine Launch Pad study in Colorectal Cancers is now closed. In the East Of England Cancer Alliance we had  5 Hospital sites participate, those being Ipswich, Colchester, Milton Keynes, MSE and Cambridge.

The Cancer Vaccine Launch Pad (CVLP) study, is now supporting a cancer vaccine trial in unresectable recurrent/unresectable metastatic Head and Neck Squamous Cell Carcinoma (HNSCC). This is a research project and so to activate as a CVLP site Trusts would need their R&D department to issue confirmation of capacity and capability (C&C)

The Head & Neck BNT113-01 is a phase II randomised control trial to compare BNT113-01 in combination with pembrolizumab versus pembrolizumab monotherapy as a first line therapy in patients with unresectable recurrent or unresectable metastatic HNSCC that is positive for HPV16 and expresses PD-L1. As part of the BNT113-01 study, patients will be centrally tested for HPV16 DNA and PD-L1 with results returned within 7-10 working days, which may be quicker than local testing and may help reduce the burden on your local testing facilities. We hope that in the East of England our 4 tertiary centres will be taking part: Norwich, Cambridge, Luton and Mid & South Essex.

EUROPAC information sheet / HCP information sheet

EUROPAC website

EUROPAC Patient letter

EMIS referral form

EUROPAC navigators

EUROPAC referral sheet

EUROPAC Report - September 2025

The NHS Jewish BRCA Testing Programme closed on 31st  October 2025. Updates will follow accordingly.

NHS Jewish BRCA Testing Programme

East Genomics - Circulating Tumour DNA (ctDNA)

North Thames Genomics - ctDNA project explained

North Thames Genomics - circulating tumour dna ctdna

East Genomics - Phase III ctDNA Lung Cancer Program Overview

East GMSA - ctDNA Lung Cancer Pilot Phase III Performance Data April '24-March '25

Marsden360 ctDNA Pathway - Pilot Phase 3 SOP