​​​​​​​​​The East of England Cancer Alliance along with two other Cancer Alliances (Wessex and Lancs & South Cumbria) partnered with Cyted Health on an SBRI funded project called Cytoprime 2 which ran from January 2023 to March 2025, see SBRI HealthcareCytoprime 2 delivers community-based clinics that build on the success of existing hospital services to help diagnose oesophageal cancer earlier.

GP practices taking part in the project identified eligible people based on their symptoms and medication history. People were contacted and offered a Capsule sponge test. Patients on a Barretts Surveillance list at participating sites within the project were also offered a capsule sponge test in their local community diagnostic centre as part of their regular surveillance protocol. 

The project is being evaluated to understand more about the use of Capsule sponge testing in people who are on regular prescriptions for heartburn and within the surveillance protocol for people already identified with Barretts Oesophagus. This is to inform future decisions on its use. East of England Cancer Alliance hosted a regional symposium in February 2025 on the use of capsule sponge in the East of England and the early findings from the Cytoprime 2 pilot. 

Patient information leaflets​​​​​​ for Heartburn Health Checks are available on this page to download and print.

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Animation on Heartburn Health Check